So far, mostly good. Syncing my Bold is much quicker with 2.0 of Missing Sync compared to 1.0.3. I had to set Missing Sync to overwrite device contacts for the first sync since it failed during an initial 2-way sync. Thereafter all was fine. iCal syncing worked fine along with tasks and Mark/Space Notebook.
Still haven't tried iTunes syncing yet. SMS syncing failed with an "unknown database error", will have to twiddle with that. Bluetooth syncing worked fine with my Mac Pro, including proximity syncing (you can set the sync interval anywhere from an overzealous 1 minute up to 8 hours or disable it if you wish).